epigenetic chemical library Search Results


epigenetic library  (Selleck Chemicals)
94
Selleck Chemicals epigenetic library
Figure 1. Alveolar organoid screen to identify <t>epigenetic</t> pathways regulating alveolar regeneration (A) Schematic of how AT2 cells isolated from SftpcEGFP mice were used in the screen. (B) An example of fluorescent reporter detection from SftpcEGFP AT2 cells in a 96-well plate. Arrows indicate negative (water or DMSO) or positive (FGF7) controls used for the screen. (C) Results from the epigenetic small molecular inhibitor library using a Z score of 2.0 as a cutoff for a positive increase in alveolar organoid total fluorescence. Data are representative of the screening assay performed in duplicate.
Epigenetic Library, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/epigenetic+chemical+library/Epigenetics+Compound+Library/pm37595582-145-18-20
Average 94 stars, based on 1 article reviews
epigenetic library - by Bioz Stars, 2026-09
94/100 stars
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epigenetic targeted library  (Life Chemicals Inc)
92
Life Chemicals Inc epigenetic targeted library
Figure 1. Alveolar organoid screen to identify <t>epigenetic</t> pathways regulating alveolar regeneration (A) Schematic of how AT2 cells isolated from SftpcEGFP mice were used in the screen. (B) An example of fluorescent reporter detection from SftpcEGFP AT2 cells in a 96-well plate. Arrows indicate negative (water or DMSO) or positive (FGF7) controls used for the screen. (C) Results from the epigenetic small molecular inhibitor library using a Z score of 2.0 as a cutoff for a positive increase in alveolar organoid total fluorescence. Data are representative of the screening assay performed in duplicate.
Epigenetic Targeted Library, supplied by Life Chemicals Inc, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/epigenetic+chemical+library/Epigenetic+Screening+Libraries/10__1007_slash_978___1___0716___1209___5-1651-18-23
Average 92 stars, based on 1 article reviews
epigenetic targeted library - by Bioz Stars, 2026-09
92/100 stars
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Image Search Results


Figure 1. Alveolar organoid screen to identify epigenetic pathways regulating alveolar regeneration (A) Schematic of how AT2 cells isolated from SftpcEGFP mice were used in the screen. (B) An example of fluorescent reporter detection from SftpcEGFP AT2 cells in a 96-well plate. Arrows indicate negative (water or DMSO) or positive (FGF7) controls used for the screen. (C) Results from the epigenetic small molecular inhibitor library using a Z score of 2.0 as a cutoff for a positive increase in alveolar organoid total fluorescence. Data are representative of the screening assay performed in duplicate.

Journal: Stem cell reports

Article Title: DOT1L regulates lung developmental epithelial cell fate and adult alveolar stem cell differentiation after acute injury.

doi: 10.1016/j.stemcr.2023.07.006

Figure Lengend Snippet: Figure 1. Alveolar organoid screen to identify epigenetic pathways regulating alveolar regeneration (A) Schematic of how AT2 cells isolated from SftpcEGFP mice were used in the screen. (B) An example of fluorescent reporter detection from SftpcEGFP AT2 cells in a 96-well plate. Arrows indicate negative (water or DMSO) or positive (FGF7) controls used for the screen. (C) Results from the epigenetic small molecular inhibitor library using a Z score of 2.0 as a cutoff for a positive increase in alveolar organoid total fluorescence. Data are representative of the screening assay performed in duplicate.

Article Snippet: Forty-eight hours after seeding cells, medium was changed to include 10 mM of one small molecule from the epigenetic library (Selleckchem, L1900) or an equal volume of H2O or DMSO as negative controls and 50 ng/mL of Fgf7 as a positive control.

Techniques: Isolation, Screening Assay

Figure 7. Model of how Dot1l regulation of AT2-AT1 differentiation through regula- tion of OxPhos and a subset of transcrip- tion and epigenetic factors

Journal: Stem cell reports

Article Title: DOT1L regulates lung developmental epithelial cell fate and adult alveolar stem cell differentiation after acute injury.

doi: 10.1016/j.stemcr.2023.07.006

Figure Lengend Snippet: Figure 7. Model of how Dot1l regulation of AT2-AT1 differentiation through regula- tion of OxPhos and a subset of transcrip- tion and epigenetic factors

Article Snippet: Forty-eight hours after seeding cells, medium was changed to include 10 mM of one small molecule from the epigenetic library (Selleckchem, L1900) or an equal volume of H2O or DMSO as negative controls and 50 ng/mL of Fgf7 as a positive control.

Techniques: